Two MOTS-c Lots, Two Different Certificates

We sell MOTS-c in two sizes, and their certificates do not look the same. One reports purity and endotoxin; the other reports content only. Same compound, same supplier, two different-looking documents — which is a good way to see what actually drives what appears on a report, and what you should conclude when a line is missing.

The two lots side by side

MOTS-c 10mg — Janoshik report #229511, lot MS10-260829, analysed 9 September 2026:

• Content: 9.92 mg / 10.16 mg / 10.40 mg
• Purity: 98.462% / 98.562% / 98.624%
• Endotoxin: <1 EU/vial, separate report #229512

MOTS-c 40mg — Janoshik report #172243, lot MOTSC40-260601, analysed June 2026:

• Content: 44.09 mg / 42.73 mg / 43.08 mg
• No purity figure, no endotoxin analysis

Why one has purity and the other does not

Not because one lot is better. A certificate shows the tests that were commissioned for that lot. Content, purity and endotoxin are separate analyses with separate costs, and they are ordered per lot, not per product. The June lot was quantified; the September lot was quantified, assayed for purity and sent for a separate endotoxin analysis.

So a missing purity line means one thing only: purity was not measured on that lot. It does not mean the material failed, and it equally does not let anyone claim a purity figure for it. This is why the 40mg product page shows no purity figure at all rather than borrowing the 98.5% from the 10mg lot. Those are different syntheses months apart; carrying a number across would be inventing data.

Six of our twenty-five products are in that position today. You can see which on the lab results page.

Reading the content figures

10mg lot: mean 10.16 mg, so 102% of label. The spread is 9.92 to 10.40, about 4.7% around the mean — ordinary for a small fill, where the same absolute variation is a larger percentage.

40mg lot: mean 43.3 mg, 108% of label, spread about 3.1%. Over label, tighter in relative terms than the 10mg lot. That relationship — larger fills being proportionally more consistent — is normal and worth remembering when a small vial looks variable.

Run either set through the COA checker to see the arithmetic.

What 98.5% means for a 16-residue peptide

MOTS-c is a short mitochondrial-derived peptide, sixteen residues. Short chains are easier to synthesise cleanly than long ones, so a figure in the high 98s is unremarkable rather than impressive, and the interesting question is what the remaining 1.5% is. That is answered by an impurity table or the chromatogram, not by the headline percentage — see reading an HPLC result.

Note also what purity is not: it is not identity. 98.5% of the detected material eluted as one peak; whether that peak is MOTS-c is a mass question.

The endotoxin line, and its limits

The 10mg lot carries <1 EU/vial from a separate analysis, #229512. Two things follow. The result belongs to that lot only — it says nothing about the 40mg lot or any future lot. And an endotoxin figure is not a sterility statement: they are different tests answering different questions.

Checks

• Match the lot number on the vial to the report: MS10-260829 or MOTSC40-260601.
• Check whether the figure you are relying on exists on that lot’s report, rather than on the product’s other size.
• Open the report at the laboratory’s own site, not only as a seller’s PDF.
• If a supplier quotes one purity figure for every size of a compound, ask which lot it came from.

Product pages: MOTS-c 10mg and MOTS-c 40mg.

All products referenced on this site are supplied for laboratory research use only, and are not for human or veterinary use.