RT40 — Retatrutide 40mg
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Research Overview
Retatrutide (CAS 2381089-83-2), also identified in the literature as LY3437943, is a synthetic 39-residue peptide built on a GIP-analogue backbone and modified with a C20 fatty diacid chain attached through a linker at position 20. In published pharmacology it is characterised as a triple agonist — it binds and activates the glucose-dependent insulinotropic polypeptide (GIP) receptor, the glucagon-like peptide-1 (GLP-1) receptor and the glucagon receptor, which is what separates it from the single- and dual-agonist incretin analogues. The lipid chain promotes reversible albumin binding, extending circulating half-life relative to the unacylated sequence.
The sequence uses α-aminoisobutyric acid (Aib) substitutions to resist dipeptidyl peptidase-4 cleavage. Molecular formula C221H342N62O68S, average molecular weight approximately 4731 Da. It is a common reference compound in comparative incretin-receptor assay work, which is the context in which this material is offered.
Analytical summary
- Compound: retatrutide (LY3437943)
- CAS number: 2381089-83-2
- Molecular formula: C221H342N62O68S
- Class: GIP / GLP-1 / glucagon triple receptor agonist, 39 residues, C20 diacid acylated
- Purity: 99%+ by HPLC (see lot certificate of analysis)
- Presentation: 40mg × 10 vials, lyophilised
Lot and presentation
This listing is supplied as 40mg × 10 vials, lyophilised powder in sealed vials. The current lot is released at 99%+ chromatographic purity; an independent certificate of analysis (lot 260804) reporting mass by HPLC-UV against a reference standard. Peptide content and purity are reported separately because they measure different things — content is how much material is in the vial, purity is what fraction of that material is the target sequence.
Handling and storage
Lyophilised material tolerates ambient temperature in transit but should be moved to -20°C on arrival for long-term storage, protected from light and moisture. Allow a vial to reach room temperature before opening so that condensation does not settle on the powder. Once reconstituted, material of this class is normally held at 2-8°C and used within a short window; repeated freeze-thaw cycles degrade it.
Research use only
This material is supplied strictly for in-vitro laboratory research and analytical reference use by qualified professionals. It is not a drug, not a dietary supplement and not a cosmetic. It is not intended for human or veterinary use, for diagnostic purposes, or for administration to any living organism. Nothing on this page describes an effect in humans.
Lab results
Janoshik report #217472 · Lot RT40-260804 · Analysed 20 August 2026
| Retatrutide | 44.93 mg / 45.35 mg / 44.70 mg |
|---|---|
| Purity | 99.896% / 99.860% / 99.877% |
| Endotoxin | <1 EU/vial · report #217473 |
Testing is ordered by the manufacturer that produces this lot, so the laboratory names the manufacturer as its client rather than BMS Labs; the report is published unchanged. The endotoxin figure is a contamination measure only — it is not a sterility result and does not indicate suitability for use in a living organism.
Questions about this lot
- Does this lot come with a certificate of analysis?
- Yes. The lot currently shipping was analysed by Janoshik Analytical as lot RT40-260804 under report number 217472, analysed 20 August 2026. The figures are published on this page exactly as the laboratory reported them, and the report can be looked up at the laboratory itself.
- What purity does the report show?
- The report gives 99.896% / 99.860% / 99.877% by HPLC, measured on separate vials from the same lot. Purity describes what fraction of the material is the target compound; content, reported separately above, describes how much material is in the vial.
- Can I verify the report myself?
- Yes. Every report on this site links to the laboratory's own record, so the figures can be checked against Janoshik rather than against us. Our guide on verifying a Janoshik report explains which fields to compare.
- What does the endotoxin figure mean?
- Endotoxin is a measure of bacterial contamination in that lot, reported here as <1 EU/vial from a separate analysis with its own report number. It is not a sterility result and does not make the material suitable for use in a living organism.
- How should this material be stored?
- As supplied, the lyophilised powder is kept cold, sealed, dry and out of the light, and the vial is allowed to reach room temperature before it is opened, so that moisture does not condense on the cold solid. Our storage and handling guide covers the details.
- How and when does it ship?
- Orders ship from our US warehouse on the next business day after payment is confirmed on-chain, by USPS, within the United States only. US shipping is free with no minimum order, and typical transit time is three to seven business days.
- What is this material sold for?
- Laboratory and analytical research use only. It is not a medicine, not a supplement, and not for human or veterinary use. Orders are accepted on that basis.
Laboratory Disclaimer
This compound is strictly for laboratory research use only. Not for human consumption, veterinary use, or therapeutic applications. Handle with extreme caution and follow all safety protocols.