MOTS-c 40mg
$
Research Overview
MOTS-c (CAS 1627580-64-6) is a 16-amino-acid mitochondrial-derived peptide, sequence MRWQEMGYIFYPRKLR, encoded within the 12S ribosomal RNA gene (MT-RNR1) of the mitochondrial genome rather than in nuclear DNA. It was one of the first peptides shown to be translated from a short open reading frame inside a mitochondrial rRNA gene, and it is studied as a retrograde signalling molecule — a message sent from the mitochondrion outward to the nucleus.
The published literature examines its interaction with the folate-methionine cycle and with AMP-activated protein kinase signalling in cell and animal models, and reports nuclear translocation under metabolic stress. Molecular formula C101H152N28O22S2, average molecular weight approximately 2174 Da. Two methionine residues make the sequence oxidation-sensitive, which is why lot purity and storage conditions matter more here than for many comparable peptides.
Analytical summary
- Compound: MOTS-c
- CAS number: 1627580-64-6
- Molecular formula: C101H152N28O22S2
- Sequence: MRWQEMGYIFYPRKLR (16 residues)
- Purity: not reported on the current lot certificate, which quantifies content per vial
- Presentation: 40mg × 10 vials, lyophilised
Lot and presentation
This listing is supplied as 40mg × 10 vials, lyophilised powder in sealed vials. An independent certificate of analysis for the current lot (lot 260601) reports content per vial by HPLC-UV against a reference standard; a separate purity figure is not reported for this lot. Peptide content and purity are reported separately because they measure different things — content is how much material is in the vial, purity is what fraction of that material is the target sequence.
Handling and storage
Lyophilised material tolerates ambient temperature in transit but should be moved to -20°C on arrival for long-term storage, protected from light and moisture. Allow a vial to reach room temperature before opening so that condensation does not settle on the powder. Once reconstituted, material of this class is normally held at 2-8°C and used within a short window; repeated freeze-thaw cycles degrade it.
Research use only
This material is supplied strictly for in-vitro laboratory research and analytical reference use by qualified professionals. It is not a drug, not a dietary supplement and not a cosmetic. It is not intended for human or veterinary use, for diagnostic purposes, or for administration to any living organism. Nothing on this page describes an effect in humans.
Lab results
Janoshik report #172243 · Lot Motsc40-260601 · Analysed June 2026
| MOTS-c | 44.09 mg / 42.73 mg / 43.08 mg |
|---|
Testing is ordered by the manufacturer that produces this lot, so the laboratory names the manufacturer as its client rather than BMS Labs; the report is published unchanged.
Questions about this lot
- Does this lot come with a certificate of analysis?
- Yes. The lot currently shipping was analysed by Janoshik Analytical as lot Motsc40-260601 under report number 172243, analysed June 2026. The figures are published on this page exactly as the laboratory reported them, and the report can be looked up at the laboratory itself.
- Does the report include a purity figure?
- The report for this lot quantifies content per vial rather than chromatographic purity, so no purity percentage is claimed for it. Where a lot is tested for purity, the figure is published on this page and on the lab results page.
- Can I verify the report myself?
- Yes. Every report on this site links to the laboratory's own record, so the figures can be checked against Janoshik rather than against us. Our guide on verifying a Janoshik report explains which fields to compare.
- How should this material be stored?
- As supplied, the lyophilised powder is kept cold, sealed, dry and out of the light, and the vial is allowed to reach room temperature before it is opened, so that moisture does not condense on the cold solid. Our storage and handling guide covers the details.
- How and when does it ship?
- Orders ship from our US warehouse on the next business day after payment is confirmed on-chain, by USPS, within the United States only. US shipping is free with no minimum order, and typical transit time is three to seven business days.
- What is this material sold for?
- Laboratory and analytical research use only. It is not a medicine, not a supplement, and not for human or veterinary use. Orders are accepted on that basis.
Laboratory Disclaimer
This compound is strictly for laboratory research use only. Not for human consumption, veterinary use, or therapeutic applications. Handle with extreme caution and follow all safety protocols.